Diethyl Ether → HCID 178498630, compound

HRID 1579223Notes

Reaction equation

HRID 1579223 reaction equation
ClC1C=CC=C(C(OO)=[O:9])C=1.[CH3:12][S:13][CH2:14][C:15]1[C:24]([C:25]([O:27][CH3:28])=[O:26])=[N+:23]([O-:29])[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[N+:16]=1[O-:30].C(OCC)C>C(Cl)(Cl)Cl>[CH3:12][S:13]([CH2:14][C:15]1[C:24]([C:25]([O:27][CH3:28])=[O:26])=[N+:23]([O-:29])[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[N+:16]=1[O-:30])=[O:9]

Participants

5

Reactant 3

HCID 3283Diethyl EtherHCID 70297m-Chloroperbenzoic acidHCID 178498629HCID 178498629, compound

Product 1

HCID 178498630HCID 178498630, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent2×

Procedure

A solution of m-chloroperbenzoic acid (9.4 g., 0.0465 m of 85 percent material) in chloroform (75 ml.) was added dropwise to a solution of 2-methylthiomethyl-3-carbomethoxyquinoxaline 1,4-dioxide (13.0 g. 0.0465 m) in chloroform (100 ml.). The mixture was stirred for one hour and then added dropwise, with stirring, to diethyl ether (1.1 liters). The yellow solid which precipitated was filtered off, washed with diethyl ether (50 ml.) and then with hexane (100 ml.) and dried. Yield = 13.4 g., 97 percent of product: m.p. 141°-142°C.

Workup

  1. additionadded dropwise
  2. customThe yellow solid which precipitated
  3. filtrationwas filtered off
  4. washwashed with diethyl ether (50 ml.)
  5. dry with materialwith hexane (100 ml.) and dried

Sources & evidence

ORD record
ord-513d870dce3c43d4a63b2e294239e751
Source dataset
uspto-grants-1976_01
Patent number
US03931174

Reaction notes

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