Hydrogen Peroxide → HCID 21568315, compound

Participants

Reaction Steps

Evaporation of the original chloroform extract, gave colourless crystals (28g). The n.m.r. spectrum of this material indicated the presence of some of the secondary phosphine oxide, 1-oxo-1,2,3,4-tetrahydrophosphinoline. This mixture was again treated with alkaline hydrogen peroxide, and a similar work-up gave a further 25g of crystalline 1-hydroxy-1-oxo-1,2,3,4-tetrahydrophosphinoline, m.p. 142°-4°.

Provenance & Evidence