Hydrogen Peroxide → HCID 21568315, compound

HRID 1579303Notes

Reaction equation

HRID 1579303 reaction equation
[O:1]=[PH:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH2:5][CH2:4][CH2:3]1.[OH:12]O>>[OH:1][P:2]1(=[O:12])[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH2:5][CH2:4][CH2:3]1

Participants

3

Reactant 2

HCID 784Hydrogen PeroxideHCID 178527007HCID 178527007, compound

Product 1

HCID 21568315HCID 21568315, compound

Procedure

Evaporation of the original chloroform extract, gave colourless crystals (28g). The n.m.r. spectrum of this material indicated the presence of some of the secondary phosphine oxide, 1-oxo-1,2,3,4-tetrahydrophosphinoline. This mixture was again treated with alkaline hydrogen peroxide, and a similar work-up gave a further 25g of crystalline 1-hydroxy-1-oxo-1,2,3,4-tetrahydrophosphinoline, m.p. 142°-4°.

Workup

  1. customEvaporation of the original chloroform
  2. extractionextract
  3. customgave colourless crystals (28g)

Sources & evidence

ORD record
ord-0d2fece189664d2c97e447caf502aa87
Source dataset
uspto-grants-1976_01
Patent number
US03931196

Reaction notes

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