Methyl iodide → 2-[2-(p-Methoxybenzamido)benzyl]-1-methylpyridinium iodide

Participants

Reaction Steps

2'-(2-Pyridylmethyl)-p-anisanilide (9.5 g., 0.03 mole) and 0.3 mole of methyl iodide in 100 ml. of acetone is refluxed with stirring for a period of 64 hr. The reaction mixture filtered and the filter cake washed with acetone provides a 93% yield of 2-[2-(p-methoxybenzamido)benzyl]-1-methylpyridinium iodide, m.p. 184°-186°C. (corr.).

Provenance & Evidence