Hydrochloric Acid → HCID 21568423, compound

HRID 1579425Notes

Reaction equation

HRID 1579425 reaction equation
O[C:2]1[N:3]=[C:4](O)[C:5]2[C:6](=[CH:8][S:9][C:10]=2[CH3:11])[N:7]=1.C([C:18]1[C:22]([NH:23]C(N)=O)=[CH:21]SC=1C)(OCC)=O.Cl>C(O)C>[CH:22]([NH:23][C:4]1[C:5]2[C:6](=[CH:8][S:9][C:10]=2[CH3:11])[N:7]=[C:2]([NH:3][CH2:4][CH2:5][CH3:10])[N:3]=1)([CH3:21])[CH3:18]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 21568421HCID 21568421, compoundHCID 178435046HCID 178435046, compound

Product 1

HCID 21568423HCID 21568423, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The 2,4-dihydroxy-5-methyl-thieno[3,4-d]pyrimidine used above is also a new compound prepared from 3-carbethoxy-2-methyl-4-ureido-thiophene by heating under reflux with concentrated hydrochloric acid in absolute ethyl alcohol. Yield reaches 70%. M.P. 300°C.

Workup

  1. temperatureby heating
  2. customYield

Sources & evidence

ORD record
ord-aca55f8aea1045a3b9f6c79b7b805a25
Source dataset
uspto-grants-1976_01
Patent number
US03931204

Reaction notes

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