Acetic Acid → HCID 86732875, compound

HRID 1579429Notes

Reaction equation

HRID 1579429 reaction equation
CS(O[C@H:6]1[C:25]2[C@:20]([CH3:27])([CH2:21][CH2:22][C:23](=[O:26])[CH:24]=2)[C@@H:19]2[C@H:8]([C@H:9]3[C@:16]([CH3:28])([CH2:17][CH2:18]2)[C@@:12]([O:29][C:30](=[O:32])[CH3:31])([C:13](=[O:15])[CH3:14])[CH2:11][CH2:10]3)[C@H:7]1OS(C)(=O)=O)(=O)=O.[N-:38]=[N+:39]=[N-:40].[Na+].C(O)(=O)C>CO>[N:38]([C:6]1[C:25]2[C@:20]([CH3:27])([CH2:21][CH2:22][C:23](=[O:26])[CH:24]=2)[C@@H:19]2[C@H:8]([C@H:9]3[C@:16]([CH3:28])([CH2:17][CH2:18]2)[C@@:12]([O:29][C:30](=[O:32])[CH3:31])([C:13](=[O:15])[CH3:14])[CH2:11][CH2:10]3)[CH:7]=1)=[N+:39]=[N-:40]

Participants

5

Reactant 3

HCID 176Acetic AcidHCID 33557Sodium AzideHCID 86732876HCID 86732876, compound

Product 1

HCID 86732875HCID 86732875, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

In a manner similar to that described in Example 6C, treat 6β,7β-dimethanesulfonyloxy-17α-acetoxy-4-pregnene-3,20-dione with sodium azide in aqueous methanol in the presence of acetic acid. Isolate and purify the resultant product in a manner similar to that described to obtain 6-azido-17α-acetoxy-4,6-pregnadiene-3,20-dione.

Workup

  1. customIsolate
  2. custompurify the resultant product in a manner similar to

Sources & evidence

ORD record
ord-800559bfbeff4ea0b2d0e7193508ecf6
Source dataset
uspto-grants-1976_01
Patent number
US03931167

Reaction notes

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