Acetic Acid → HCID 54366785, compound

HRID 1579435Notes

Reaction equation

HRID 1579435 reaction equation
CS(O[C@H:6]1[C:30]2[C@:25]([CH3:32])([CH2:26][CH2:27][C:28](=[O:31])[CH:29]=2)[C@@H:24]2[C@H:8]([C@H:9]3[C@:21]([CH3:33])([CH2:22][CH2:23]2)[C@@H:12]([C@H:13]([CH3:20])[CH2:14][CH2:15][CH2:16][CH:17]([CH3:19])[CH3:18])[CH2:11][CH2:10]3)[C@H:7]1OS(C)(=O)=O)(=O)=O.[N-:39]=[N+:40]=[N-:41].[Na+].C(O)(=O)C>CO>[N:39]([C:6]1[C:30]2[C@:25]([CH3:32])([CH2:26][CH2:27][C:28](=[O:31])[CH:29]=2)[C@@H:24]2[C@H:8]([C@H:9]3[C@:21]([CH3:33])([CH2:22][CH2:23]2)[C@@H:12]([C@H:13]([CH3:20])[CH2:14][CH2:15][CH2:16][CH:17]([CH3:19])[CH3:18])[CH2:11][CH2:10]3)[CH:7]=1)=[N+:40]=[N-:41]

Participants

5

Reactant 3

HCID 176Acetic AcidHCID 33557Sodium AzideHCID 86732880HCID 86732880, compound

Product 1

HCID 54366785HCID 54366785, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

In a manner similar to that described in Example 6C, treat 6β,7β-dimethanesulfonyloxy-4-cholestene-3-one with sodium azide in aqueous methanol in the presence of acetic acid. Isolate and purify the resultant product in a manner similar to that described to obtain 6-azido-4,6-cholestadiene-3-one.

Workup

  1. customIsolate
  2. custompurify the resultant product in a manner similar to

Sources & evidence

ORD record
ord-f64c64f06ca943e3ac79325ca016c376
Source dataset
uspto-grants-1976_01
Patent number
US03931167

Reaction notes

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