Hydrogen Peroxide → HCID 54737945, compound

HRID 1579589Notes

Reaction equation

HRID 1579589 reaction equation
[CH2:1]([S:7][C:8]1[C:9](=[O:16])[O:10][C:11]([CH3:15])=[CH:12][C:13]=1[OH:14])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].[OH:17]O>C(O)(=O)C>[CH2:1]([S:7]([C:8]1[C:9](=[O:16])[O:10][C:11]([CH3:15])=[CH:12][C:13]=1[OH:14])=[O:17])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6]

Participants

4

Reactant 2

HCID 784Hydrogen PeroxideHCID 54730468HCID 54730468, compound

Product 1

HCID 54737945HCID 54737945, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

3-n-Hexylthio-4-hydroxy-6-methyl-2-pyrone (9.1 g., 0.040 mol), 30% hydrogen peroxide (4.85 g., 0.0440 mol), and 40 ml. glacial acetic acid were combined and stirred at room temperature over night. The clear solution was poured into 200 ml. ice water and the resulting white precipitate was collected and dried in vacuo: m.p. 59°-60°C. The solid was recrystallized from n-hexane to recover 8.0 g. (77%) of the desired compound as white crystalline platelets, m.p. 59°-60°C.

Workup

  1. additionThe clear solution was poured into 200 ml
  2. customice water and the resulting white precipitate was collected
  3. customdried in vacuo
  4. customThe solid was recrystallized from n-hexane
  5. customto recover 8.0 g

Sources & evidence

ORD record
ord-b0d99447a442498a8234d32c5dc4dfab
Source dataset
uspto-grants-1976_01
Patent number
US03931235

Reaction notes

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