Hydrochloric Acid → HCID 21568951, compound

HRID 1579628Notes

Reaction equation

HRID 1579628 reaction equation
[CH3:1][C:2]1[C:10]2[O:11][C:12]([C:14]([OH:16])=[O:15])=[CH:13][C:9]=2[C:8]2[CH2:7][C:6](Br)([CH:17]([CH3:19])[CH3:18])[C:5](=[O:21])[C:4]=2[C:3]=1[CH3:22].C1CN2C(=NCCC2)C1.Cl>CS(C)=O>[CH3:1][C:2]1[C:10]2[O:11][C:12]([C:14]([OH:16])=[O:15])=[CH:13][C:9]=2[C:8]2[CH:7]=[C:6]([CH:17]([CH3:18])[CH3:19])[C:5](=[O:21])[C:4]=2[C:3]=1[CH3:22]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 763491,5-Diazabicyclo(4.3.0)non-5-eneHCID 215689584,5-dimethyl-6-oxo-7,8-dihydro-7-bromo-7-isopropyl-6H-indeno[5,4-b]furan-2-carboxylic acid

Product 1

HCID 21568951HCID 21568951, compound

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Conditions

Temperature
25 °C

Procedure

A solution of 4,5-dimethyl-6-oxo-7,8-dihydro-7-bromo-7-isopropyl-6H-indeno[5,4-b]furan-2-carboxylic acid (0.01 mole) in dimethylsulfoxide (50 ml.) is treated with 1,5-diazabicyclo[4.3.0] -5-nonene (0.20 mole) and stirred in an inert (nitrogen) atmosphere at 25°C. for 1 hour; poured into 1.0 N hydrochloric acid to afford 4,5-dimethyl-6-oxo-7-isopropyl-6H-indeno-[5,4-b]furan-2-carboxylic acid.

Sources & evidence

ORD record
ord-83432dfd4971486687b0129425e3fda2
Source dataset
uspto-grants-1976_01
Patent number
US03931239

Reaction notes

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