反应详情

温度

40 °C

120 ml of 37 percent by weight aqueous hydrochloric acid and 42 g (0.21 mol) of iron (II) chloride tetrahydrate are introduced into a reaction vessel and saturated with approximately 8 g of gaseous hydrogen chloride. 11 g of 5-nitro-1,4-naphthoquinone-1-oxime are introduced at a temperature of about 20° to 25°C. The reaction mixture is kept at the temperature indicated with stirring and, after 2 hours, is poured into 1,000 ml of water heated to approximately 40°C. followed by stirring for 30 minutes. The reaction product precipitated is then filtered off under suction, washed with water until neutral and dried at approximately 50°C. 5-Nitro-1,4-naphthoquinone melting at 161°C is thus obtained in a yield of 9.8 g (96 percent of the theoretical yield).

1. stirringby stirring for 30 minutes
2. customThe reaction product precipitated
3. filtrationis then filtered off under suction
4. washwashed with water until neutral and
5. customdried at approximately 50°C