Chloroacetonitrile → 2-(2-Benzothiazolylthio)acetonitrile

In a 1 liter flask were combined 33.4 g. (0.2 mole) of 2-mercaptobenzothiazole and 22.4 g. (0.2 mole) of potassium t-butoxide with 300 ml. of tetrahydrofuran. The reaction mass was stirred at room temperature for 15 minutes. Chloroacetonitrile, 16 g. (0.2 mole) was added and the resulting mixture was stirred at room temperature for 1 hour. The mixture was then poured into 400 ml. of benzene and was washed with three 250 ml. portions of water. The benzene phase was dried with anhydrous magnesium sulfate. The solvent was evaporated. There was obtained a yield of 37.2 g. of the title compound, m.p. 75°-77°C.

1. customIn a 1 liter flask were combined
2. addition(0.2 mole) was added
3. stirringthe resulting mixture was stirred at room temperature for 1 hour
4. additionThe mixture was then poured into 400 ml
5. washof benzene and was washed with three 250 ml
6. dry with materialThe benzene phase was dried with anhydrous magnesium sulfate
7. customThe solvent was evaporated
8. customThere was obtained a yield of 37.2 g

ORD record

ord-ebef64584e84445ea77f0ef1d5a0d7a8

Source dataset

uspto-grants-1976_01

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US03931358