Ethyl (6-methoxynaphthalen-2-yl)(oxo)acetate → HCID 21569133, compound

HRID 1579827Notes

Reaction equation

HRID 1579827 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[CH:9]=[C:8]([C:13](=[O:19])[C:14]([O:16][CH2:17][CH3:18])=[O:15])[CH:7]=[CH:6]2.[H][H]>[Pt]=O.C(O)(C)C>[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[CH:9]=[C:8]([CH:13]([OH:19])[C:14]([O:16][CH2:17][CH3:18])=[O:15])[CH:7]=[CH:6]2

Participants

5

Reactant 2

HCID 20433897Ethyl (6-methoxynaphthalen-2-yl)(oxo)acetateHCID 178418361HCID 178418361, compound2×

Product 1

HCID 21569133HCID 21569133, compound

Reagents, catalysts & solvents 2

HCID 82844Platinum oxide (PtO)CatalystHCID 3776IsopropanolSolvent

Procedure

Into a Paar hydrogenation bottle is added 0.144 mole of ethyl 6-methoxy-2-naphthylglyoxylate, 2 ml. of 0.1 M - ferrous sulfate solution; 220 ml. of isopropanol, and 1.0 g. of 84.1% platinum oxide. The mixture is shaken for 2 hours at room temperature with hydrogen gas until 0.144 mole of hydrogen is absorbed. The catalyst is then filtered off and the solution is evaporated in vacuo and the residue fractionally distilled to obtain ethyl 6-methoxy-2-naphthylglycolate.

Workup

  1. customis absorbed
  2. filtrationThe catalyst is then filtered off
  3. customthe solution is evaporated in vacuo
  4. distillationthe residue fractionally distilled

Sources & evidence

ORD record
ord-a454e5e415ac48cfad5db29245203947
Source dataset
uspto-grants-1976_01
Patent number
US03931269

Reaction notes

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