HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminosalicylic Acid → HCID 12270274, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminosalicylic Acid | HCID 4649 | — |
| Reactant | 2-(2-Oxo-2-phenylethyl)cyclohexanone | HCID 10512899 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 12270274 | HCID 12270274 | — |
Reaction Steps
A solution of 32.4 g. (0.15 mole) of 2-phenacylcyclohexanone, 23.0 g. (0.15 mole) of 4-aminosalicylic acid and 90 ml. of glacial acetic acid was heated under reflux for 7 hours, cooled, diluted with 90 ml. of water and extracted with ether. The ether solution was dried over sodium sulfate and concentrated. The residue was recrystallized from benzene-ethanol to provide 3.36 g. (7%) of yellow crystals, m.p. 193°-195°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03931407 |
| Source dataset | uspto-grants-1976_01 |
| ORD ID | ord-4c6d588b6ff34bcd90462c14938fcc72 |
| Source note | uspto-grants-1976_01 |