反应详情

A mixture of 25.0 g. (0.075 mole) of 1-(3-carboxy-4-hydroxyphenyl)-2-phenyl-4,5,6,7-tetrahydroindole and 225 g. (2.25 mole) of acetic anhydride was heated under reflux for 3 hours, diluted with 200 ml. of tetrahydrofuran, and poured into 3 l. of water. An oil separated and slowly solidified. Recrystallization from acetic acid gave a tan solid, m.p. 155°-162°.

1. additionA mixture of 25.0 g
2. temperatureunder reflux for 3 hours
3. additiondiluted with 200 ml
4. customAn oil separated
5. customRecrystallization from acetic acid
6. customgave a tan solid, m.p. 155°-162°