反应详情

A mixture of 16.6 g. (0.063 mole) of 1-phenacyl-2-tetralone, 9.65 g. (0.063 mole) of 5-aminosalicylic acid, and 60 ml. of glacial acetic acid was heated under reflux under nitrogen for 2 hours, cooled and filtered. The collected solid was washed with acetic acid and water, dried and recrystallized from acetic acid to provide 16.3 g. (68%) of crystals, m.p. 223°-225°.

1. additionA mixture of 16.6 g
2. temperatureunder reflux under nitrogen for 2 hours
3. temperaturecooled
4. filtrationfiltered
5. washThe collected solid was washed with acetic acid and water
6. customdried
7. customrecrystallized from acetic acid
8. customto provide 16.3 g