反应详情

A mixture of 26.2 g. (0.069 mole) of 3-(3-carboxy-4-hydroxyphenyl)-4,5-dihydro-2-phenylbenz[e]indole and 204 g. of acetic anhydride was stirred at 75° for 4 hours, cooled, treated with 34 g. of water, stirred for several hours until a solution formed, and allowed to stand overnight. The solid which separated was collected, washed with acetic acid and petroleum ether, and dried to provide 26.7 g. (91%) of crystals, m.p. 194°-196°.

1. additionA mixture of 26.2 g
2. temperaturecooled
3. additiontreated with 34 g
4. customformed
5. customThe solid which separated
6. customwas collected
7. washwashed with acetic acid and petroleum ether
8. customdried
9. customto provide 26.7 g