Ammonia → HCID 54284920, compound

HRID 1579977Notes

Reaction equation

HRID 1579977 reaction equation
BrBr.[C:3]([C:5]([C:21]([O:23][CH2:24][CH3:25])=[O:22])=[N:6][CH:7]=[C:8](N1CCOCC1)[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)#[N:4].C(Cl)Cl.N>C(O)C>[C:3]([C:5]([C:21]([O:23][CH2:24][CH3:25])=[O:22])=[N:6][CH:7]=[CH:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)#[N:4]

Participants

6

Reactant 4

HCID 222AmmoniaHCID 6344DichloromethaneHCID 24408BromineHCID 54233514HCID 54233514, compound

Product 1

HCID 54284920HCID 54284920, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A reactor provided with a stirring device, a bromine feed and a calcium chloride tube, is filled with a solution of 6.3 parts of 1-cyano-1-ethoxycarbonyl-4-morpholino-4-phenyl-2-aza-1,3-butadiene in 63 parts by volume of dry methylene chloride. 1.4 parts by weight of ammonia (in the form of a concentrated solution in ethanol) are added at the ambient temperature over a period of three days.

Workup

  1. customA reactor provided with a stirring device

Sources & evidence

ORD record
ord-5c64e23592a341fcb0cb7c1ee3374964
Source dataset
uspto-grants-1976_01
Patent number
US03932404

Reaction notes

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