HCID 54233514, compound → HCID 73186001, compound

HRID 1579979Notes

Reaction equation

HRID 1579979 reaction equation
[C:1]([C:3]([C:19]([O:21][CH2:22]C)=[O:20])=[N:4][CH:5]=[C:6]([N:13]1CCOCC1)[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)#[N:2].C(C(OC)=NC=C(N1CCOCC1)C1C=CC=CC1=C=O)#N>>[C:1]([C:3]([C:19]([O:21][CH3:22])=[O:20])=[N:4][CH:5]=[C:6]([NH2:13])[C:7]1[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=1)#[N:2]

Participants

3

Reactant 2

HCID 54233514HCID 54233514, compoundHCID 86732918HCID 86732918, compound

Product 1

HCID 73186001HCID 73186001, compound

Procedure

One operates as in Example 12, but the 6.3 parts of 1-cyano-1-ethoxycarbonyl-4-morpholino-4-phenyl-2-aza-1,3-butadiene are replaced by 6 parts of 1-cyano-1-methoxy-carbonyl-4-morpholino-4-phenyl-2-aza-1,3-butadiene. 3.7 parts of 1-cyano-1-methoxycarbonyl-4-amino-4-phenyl-2-aza-1,3-butadiene are obtained. After recrystallisation from methanol, the product melts at 186°C.

Sources & evidence

ORD record
ord-f12765bbb7a64459bbae0e85854a91d5
Source dataset
uspto-grants-1976_01
Patent number
US03932404

Reaction notes

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