Piperidine, 1-(3-chloropropyl)- → Bis(3-piperidinopropyl) 9-ethylcarbazole-3,6-dicarboxylate dihydrochloride

HRID 1580166Notes

Reaction equation

HRID 1580166 reaction equation
[CH2:1]([N:3]1[C:15]2[CH:14]=[CH:13][C:12]([C:16]([OH:18])=[O:17])=[CH:11][C:10]=2[C:9]2[C:4]1=[CH:5][CH:6]=[C:7]([C:19]([OH:21])=[O:20])[CH:8]=2)[CH3:2].[N:22]1([CH2:28][CH2:29][CH2:30][Cl:31])[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]1>[Cl-].C([N+](C)(C)C)C1C=CC=CC=1>[ClH:31].[ClH:31].[CH2:1]([N:3]1[C:15]2[CH:14]=[CH:13][C:12]([C:16]([O:18][CH2:30][CH2:29][CH2:28][N:22]3[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]3)=[O:17])=[CH:11][C:10]=2[C:9]2[C:4]1=[CH:5][CH:6]=[C:7]([C:19]([O:21][CH2:30][CH2:29][CH2:28][N:22]1[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]1)=[O:20])[CH:8]=2)[CH3:2]

Participants

4

Reactant 2

HCID 79625Piperidine, 1-(3-chloropropyl)-HCID 37979149-ethyl-9H-carbazole-3,6-dicarboxylic acid

Product 1

HCID 21419565Bis(3-piperidinopropyl) 9-ethylcarbazole-3,6-dicarboxylate dihydrochloride

Reagents, catalysts & solvents 1

HCID 5963Benzyltrimethylammonium chlorideCatalyst

Procedure

By the procedure of Example 2, one equivalent of 9-ethylcarbazole-3,6-dicarboxylic acid is allowed to react with two equivalents of 3-piperidinopropyl chloride in the presence of a catalytic amount of benzyltrimethylammonium chloride to give the product.

Workup

  1. customto give the product

Sources & evidence

ORD record
ord-38c572beb6c0498fac2171831f17ca49
Source dataset
uspto-grants-1976_01
Patent number
US03932456

Reaction notes

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