HCID 54557719, compound → HCID 131709905, compound

HRID 1580175Notes

Reaction equation

HRID 1580175 reaction equation
[CH3:1][C:2]1([CH3:30])[CH:29]2[C:24]([CH2:25][NH:26][CH2:27][CH2:28]2)=[C:5]2[C:6]([OH:23])([OH:22])[CH:7]=[C:8]([CH:10]([CH3:21])[CH2:11][CH2:12][CH2:13][C:14]3[CH:19]=[CH:18][C:17]([F:20])=[CH:16][CH:15]=3)[CH:9]=[C:4]2[O:3]1.Cl[CH2:32][CH:33]=[CH:34][C:35]1[CH:40]=[C:39]([O:41][CH3:42])[C:38]([O:43][CH3:44])=[C:37]([O:45][CH3:46])[CH:36]=1>CN(C)C=O>[CH3:30][C:2]1([CH3:1])[CH:29]2[C:24]([CH2:25][N:26]([CH2:32][CH:33]=[CH:34][C:35]3[CH:36]=[C:37]([O:45][CH3:46])[C:38]([O:43][CH3:44])=[C:39]([O:41][CH3:42])[CH:40]=3)[CH2:27][CH2:28]2)=[C:5]2[C:6]([OH:22])([OH:23])[CH:7]=[C:8]([CH:10]([CH3:21])[CH2:11][CH2:12][CH2:13][C:14]3[CH:19]=[CH:18][C:17]([F:20])=[CH:16][CH:15]=3)[CH:9]=[C:4]2[O:3]1

Participants

4

Reactant 2

HCID 54557719HCID 54557719, compoundHCID 131709901HCID 131709901, compound

Product 1

HCID 131709905HCID 131709905, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

5,5-Dimethyl-8-(4-p-fluorophenyl-1-methylbutyl)-10-hydroxy-1,2,3,4-tetrahydro-5H[1]benzopyrano[4,3-c]pyridin-10-ol (1 mole) and 1-(3-chloropropenyl)3,4,5-trimethoxybenzene (0.5 mole) were reacted in dimethylformamide as described in Example 7 to give the desired product.

Sources & evidence

ORD record
ord-ab76865a4767419ea5d2a9bbbad892d7
Source dataset
uspto-grants-1976_01
Patent number
US03932432

Reaction notes

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