Phenol → 4-tert-Butylphenol

HRID 1580419Notes

Reaction equation

HRID 1580419 reaction equation
C([C:5]1[CH:10]=[C:9]([C:11]([CH3:14])([CH3:13])[CH3:12])[CH:8]=[CH:7][C:6]=1[OH:15])(C)(C)C.C1(O)C=CC=CC=1.C1(S(O)(=O)=O)C=CC=C(S(O)(=O)=O)C=1>>[C:11]([C:9]1[CH:10]=[CH:5][C:6]([OH:15])=[CH:7][CH:8]=1)([CH3:14])([CH3:12])[CH3:13]

Participants

4

Reactant 3

HCID 996PhenolHCID 73112,4-Di-tert-butylphenolHCID 7388Benzene-1,3-disulfonic acid

Product 1

HCID 73934-tert-ButylphenolYield 81.2%

Procedure

Thus, to 2.06 grams of 2,4-ditertiary-butyl phenol was added 0.94 grams of phenol. Then 1% of meta-benzenedisulfonic acid was stirred in with warming and the final mixture was heated to 150°C. for 1.5 hours. Analysis gave 81.2% para-tertiary-butyl phenol. The remaining components were its isomers.

Workup

  1. temperaturewith warming

Sources & evidence

ORD record
ord-e67f234355064b96835abea4102bdc16
Source dataset
uspto-grants-1976_01
Patent number
US03932537

Reaction notes

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