Peracetic Acid → HCID 178504624, compound

HRID 1580435Notes

Reaction equation

HRID 1580435 reaction equation
[C:1]1([N:7]2[C:11]([S:12][CH3:13])=[N:10][C:9]([OH:14])=[N:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C(OO)(=[O:17])C>C(OCC)(=O)C.C(O)(=O)C>[C:1]1([N:7]2[C:11]([S:12]([CH3:13])=[O:17])=[N:10][C:9]([OH:14])=[N:8]2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

5

Reactant 2

HCID 6585Peracetic AcidHCID 178503577HCID 178503577, compound

Product 1

HCID 178504624HCID 178504624, compound

Reagents, catalysts & solvents 2

HCID 176Acetic AcidSolventHCID 8857Ethyl AcetateSolvent

Conditions

Temperature
50 °C

Procedure

An amount of 41.4 g of 1-phenyl-5-methylmercapto-3-hydroxy-1,2,4-triazole is suspended at 50°C in 400 ml of ethyl acetate. An addition is then made dropwise, within 15 minutes, of 60 ml of a 60% solution of peroxyacetic acid in glacial acetic acid at 45°-50°C. After completion of the addition, the solution is stirred for 2 hours at 50°C, and the cooled to 20°C. The precipitated product is filtered off, washed with water, and dried in vacuo. The resulting product is 1-phenyl-5-methylsulphinyl-3-hydroxy-1,2,4-triazole in the form of white crystals, M.P. 180°-182°C.

Workup

  1. additionAn addition
  2. additionAfter completion of the addition
  3. temperaturethe cooled to 20°C
  4. filtrationThe precipitated product is filtered off
  5. washwashed with water
  6. customdried in vacuo

Sources & evidence

ORD record
ord-ad9aaafb47e94b479b4a0cd6fb435546
Source dataset
uspto-grants-1976_01
Patent number
US03932630

Reaction notes

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