Dipropylamine → HCID 178457187, compound

Participants

Reaction Steps

5g 7-chloro-3-chloromethyl-1-phenyl-benzo-1,2,4-thiadiazine-1-oxide and 20 g di-n-propylamine are dissolved in 80 ml methanol and left standing for 12 hours at room temperature. Thereafter the solution is evaporated and the residue distributed between chloroform and water. The chloroform phase is extracted with water several times, dried, evaporated, and the base (oil) dissolved in ethanol. After addition of ethanolic hydrochloric acid, the dihydrochloride precipitates. M.p. 192°-195° (decompn.).

Provenance & Evidence