Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Potassium Cyanide | HCID 9032 | — |
| Reactant | Methanone, (4-nitrophenyl)phenyl- | HCID 70839 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 12503203 | HCID 12503203 | — |
Reaction Steps
A mixture of dry powdered potassium cyanide (4g.) and 4-nitrobenzophenone (2.27g) was suspended in dimethylsulphoxide (40 ml.) and heated for 4 hours at 100°C. with occasional agitation. The solution was then poured into water and the insoluble neutral fraction removed by filtration. After acidification the filtrate was extracted with ether and the 5-benzoylsalicylonitrile thus obtained was crystallised from aqueous ethanol to give needles, m.p. 185°-186°C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US03933807 |
|---|
| Source dataset | uspto-grants-1976_01 |
|---|
| ORD ID | ord-73d71c1827c743709d2fc8b0843c8efb |
|---|
| Source note | uspto-grants-1976_01 |
|---|
