Formaldehyde → HCID 54136349, compound

HRID 1580568Notes

Reaction equation

HRID 1580568 reaction equation
[O:1]1[CH2:6][CH2:5][N:4]([CH2:7][CH:8]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][N:13]=2)[C:9]([NH2:11])=[S:10])[CH2:3][CH2:2]1.[NH:18]1[CH2:22][CH2:21][CH2:20][CH2:19]1.[CH2:23]=O>CO>[O:1]1[CH2:6][CH2:5][N:4]([CH2:7][CH:8]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][N:13]=2)[C:9]([NH:11][CH2:23][N:18]2[CH2:22][CH2:21][CH2:20][CH2:19]2)=[S:10])[CH2:3][CH2:2]1

Participants

5

Reactant 3

HCID 712FormaldehydeHCID 31268PyrrolidineHCID 53838371HCID 53838371, compound

Product 1

HCID 54136349HCID 54136349, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The above prepared 3-morpholino-2-(2-pyridyl)thiopropanamide is reacted with pyrrolidine and formaldehyde in methanol by the procedure of Example 2 to give 3-morpholino-N-pyrrolidinomethyl-2-(2-pyridyl)thiopropanamide.

Sources & evidence

ORD record
ord-7ef731f13da54f2db788b22f34b062ee
Source dataset
uspto-grants-1976_01
Patent number
US03933811

Reaction notes

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