Hydrochloric Acid → 4-[(Pyridin-2-yl)sulfanyl]benzene-1,2-diamine

HRID 1580957Notes

Reaction equation

HRID 1580957 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=2)=[CH:4][C:3]=1[N+:15]([O-])=O.Cl.C(=O)(O)[O-].[K+]>>[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=2)=[CH:4][C:3]=1[NH2:15]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 516893Potassium BicarbonateHCID 214827702-Nitro-4-[(pyridin-2-yl)sulfanyl]aniline

Product 1

HCID 214827934-[(Pyridin-2-yl)sulfanyl]benzene-1,2-diamine

Procedure

2.3 G. of 1-amino-2-nitro-4-(pyrid-2-ylthio)benzene in 12 ml. concentrated hydrochloric acid is treated with 12 g. of stannous chloride on the steam bath for 15 minutes. The cooled solution is treated with an excess of potassium bicarbonate and extracted with chlorofrom and filtered. The chloroform layer is separated, dried and evaporated to yield 1,2-diamino-4-(pyrid-2-ylthio)benzene.

Workup

  1. extractionextracted with chlorofrom
  2. filtrationfiltered
  3. customThe chloroform layer is separated
  4. customdried
  5. customevaporated

Sources & evidence

ORD record
ord-682bb6378d9445ae913ff34afacdcf14
Source dataset
uspto-grants-1976_01
Patent number
US03935209

Reaction notes

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