Methanol → 1H-1-Benzazepine

HRID 158097Notes

Reaction equation

HRID 158097 reaction equation
[CH3:13][OH:14].[NH:1]1[C:2]([OH:12])=[CH:3][CH:4]=[CH:5][c:6]2[c:7]1[cH:8][cH:9][cH:10][cH:11]2.[OH-:22].[OH-:24].[OH:15][C:16]([C:17]([F:18])([F:19])[F:20])=[O:21].[Pd+2:23]>>[NH:1]1[CH:2]=[CH:3][CH:4]=[CH:5][c:6]2[c:7]1[cH:8][cH:9][cH:10][cH:11]2

Participants

6

Reactant 5

HCID 887MethanolHCID 961Hydroxide2×HCID 6422Trifluoroacetic acidHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 21618893Benzazepinol

Product 1

HCID 155596581H-1-Benzazepine

Sources & evidence

ORD record
ord-84b7ea3f92764d03a1b038021a54adaa
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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