Acetone → HCID 21560899, compound

HRID 1580990Notes

Reaction equation

HRID 1580990 reaction equation
[CH3:1][C:2]1[C:19]([CH3:20])=[CH:18][C:5]2[CH:6](C3C=CC=CC=3)[NH:7][CH2:8][CH2:9][NH:10][CH2:11][C:4]=2[CH:3]=1.CC(C)=[O:23].Cl([O-])(=O)=O.[K+]>O>[CH3:1][C:2]1[CH:3]=[C:4]2[C:5](=[CH:18][C:19]=1[CH3:20])[C:6]1=[N:7][CH2:8][CH2:9][N:10]1[CH:11]2[OH:23]

Participants

5

Reactant 3

HCID 180AcetoneHCID 6426889Potassium ChlorateHCID 21560917HCID 21560917, compound

Product 1

HCID 21560899HCID 21560899, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Four grams of 1,2,3,4,5,6-hexahydro-8,9-dimethyl1-phenyl-2,5-benzodiazocine is dissolved in 100 ml. of acetone. A solution of 2 g. of potassium chlorate in 100 ml. of water is added dropwise over a period of an hour. Thereafter, the mixture is filtered and evaporated to dryness to afford 2,3-dihydro-7,8-dimethyl-5H-imidazo[2,1-a]isoindol-5-ol which is recrystallized from methanol.

Workup

  1. filtrationThereafter, the mixture is filtered
  2. customevaporated to dryness

Sources & evidence

ORD record
ord-6805488a139f475d9968bae4899b427f
Source dataset
uspto-grants-1976_01
Patent number
US03935218

Reaction notes

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