Ethyl (imidazolidin-2-ylidene)acetate → HCID 68144108, compound

HRID 1580997Notes

Reaction equation

HRID 1580997 reaction equation
C(O[C:4](=O)[CH2:5][C:6]([CH:8]=[CH:9][C:10]1[S:14][CH:13]=[CH:12][CH:11]=1)=O)C.[C:16]([CH:21]=[C:22]1[NH:26][CH2:25][CH2:24][NH:23]1)([O:18][CH2:19][CH3:20])=[O:17]>C(O)C>[CH2:19]([O:18][C:16]([C:6]1[CH:8]([CH2:9][C:10]2[S:14][CH:13]=[CH:12][CH:11]=2)[C:21]([C:16]([O:18][CH2:19][CH3:20])=[O:17])=[C:22]2[NH:23][CH2:24][CH2:25][N:26]2[C:5]=1[CH3:4])=[O:17])[CH3:20]

Participants

4

Reactant 2

HCID 12377942Ethyl (imidazolidin-2-ylidene)acetateHCID 53707123HCID 53707123, compound

Product 1

HCID 68144108HCID 68144108, compoundYield 72%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

Boiling a solution of 7.4 g of then-2-ylideneacetoacetic acid ethyl ester and 5.2 g of 2-carbethoxymethylideneimidazolidine in 60 ml of ethanol for 6 hours yields 5-methyl-7-(then-2-yl)-1,2,3,7-tetrahydroimidazolo[1,2-a]pyridine-6,8-dicarboxylic acid diethyl ester of melting point 134°C (ethanol).

Workup

  1. customfor 6 hours

Sources & evidence

ORD record
ord-aa8c4b65713d4a3b9150a0f31aabeb57
Source dataset
uspto-grants-1976_01
Patent number
US03935220

Reaction notes

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