Triphenylphosphine → 2-Oxo-3-ethylheptyltriphenylphosphonium chloride

HRID 1581111Notes

Reaction equation

HRID 1581111 reaction equation
[Cl:1][CH2:2][C:3](=[O:11])[CH:4]([CH2:9][CH3:10])[CH2:5][CH2:6][CH2:7][CH3:8].[C:12]1([P:18]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>C(Cl)(Cl)Cl>[Cl-:1].[O:11]=[C:3]([CH:4]([CH2:9][CH3:10])[CH2:5][CH2:6][CH2:7][CH3:8])[CH2:2][P+:18]([C:19]1[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=1)([C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1)[C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1

Participants

4

Reactant 2

HCID 11776TriphenylphosphineHCID 203007081-Chloro-3-ethylheptan-2-one

Product 1

HCID 215614842-Oxo-3-ethylheptyltriphenylphosphonium chlorideYield 129.9%

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

A solution of 1-chloro-3-ethyl-2-heptanone (88.4 g.) and triphenylphosphine (81 g.) in chloroform (100 ml.) was saturated with nitrogen and refluxed under nitrogen overnight. The chloroform was removed in vacuo to give crude 2-oxo-3-ethylheptyltriphenylphosphonium chloride (176.1 g.).

Workup

  1. temperaturerefluxed under nitrogen overnight
  2. customThe chloroform was removed in vacuo

Sources & evidence

ORD record
ord-0c6e81f577624b608dc6acd6a77271f7
Source dataset
uspto-grants-1976_01
Patent number
US03935261

Reaction notes

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