p-Anisoyl chloride → HCID 21561634, compound

HRID 1581130Notes

Reaction equation

HRID 1581130 reaction equation
Cl.[OH:2][CH2:3][C:4]1[CH:5]=[C:6]([OH:11])[C:7]([CH3:10])=[N:8][CH:9]=1.[C:12](Cl)(=[O:21])[C:13]1[CH:18]=[CH:17][C:16]([O:19][CH3:20])=[CH:15][CH:14]=1>N1C=CC=CC=1>[OH:2][CH2:3][C:4]1[CH:5]=[C:6]([O:11][C:12](=[O:21])[C:13]2[CH:18]=[CH:17][C:16]([O:19][CH3:20])=[CH:15][CH:14]=2)[C:7]([CH3:10])=[N:8][CH:9]=1

Participants

4

Reactant 2

HCID 7477p-Anisoyl chlorideHCID 1991873-Pyridinemethanol, 5-hydroxy-6-methyl-, hydrochloride

Product 1

HCID 21561634HCID 21561634, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

To a solution of 0.9 g. of 5-hydroxymethyl-2-methyl-3-pyridinol hydrochloride in 5 ml. of anhydrous pyridine was added 0.86 g. of p-anisoyl chloride dropwise under cooling. After standing overnight the resulting mixture was poured into ice water and extracted with chloroform.

Workup

  1. extractionextracted with chloroform

Sources & evidence

ORD record
ord-15bcc5cc87684b72b11f6ed65c6b3fbf
Source dataset
uspto-grants-1976_01
Patent number
US03935311

Reaction notes

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