(5S)-5-(Aminomethyl)-3-(3-fluoro-4-(4-morpholinyl)phenyl)-2-oxazolidinone → HCID 178464373, compound

HRID 1581159Notes

Reaction equation

HRID 1581159 reaction equation
CC(Cl)c1cccnc1.NC[C@H]1CN(c2ccc(N3CCOCC3)c(F)c2)C(=O)O1>CN(C)C=O.O=C([O-])[O-].[Cs+].[Cs+].[I-].[K+]>CC(NC[C@H]1CN(c2ccc(N3CCOCC3)c(F)c2)C(=O)O1)c1cccnc1

Participants

6

Reactant 2

HCID 10780199(5S)-5-(Aminomethyl)-3-(3-fluoro-4-(4-morpholinyl)phenyl)-2-oxazolidinoneHCID 149329503-(1-Chloroethyl)pyridine

Product 1

HCID 178464373HCID 178464373, compound

Reagents, catalysts & solvents 3

HCID 4875Potassium IodideReagentHCID 10796Cesium carbonateReagentHCID 6228DimethylformamideSolvent3×

Conditions

Temperature
70 °C

Workup

  1. aliquotNo procedure recorded
  2. additionDilution of the aliquot (2 uL) with DMSO (200 uL).

Sources & evidence

ORD record
ord-c4e5e6a9c3b644d1b10f12f1d37d5052
Source dataset
Fig 7 data from Golden paper
Original link
View source

Reaction notes

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