5-Methoxy-1,2,3,4-tetrahydroisoquinoline → HCID 178488322, compound

HRID 1581219Notes

Reaction equation

HRID 1581219 reaction equation
CC(Cl)c1cccnc1.COc1cccc2c1CCNC2>CN(C)C=O.O=C([O-])[O-].[Cs+].[Cs+].[I-].[K+]>COc1cccc2c1CCN(C(C)c1cccnc1)C2

Participants

6

Reactant 2

HCID 139482495-Methoxy-1,2,3,4-tetrahydroisoquinolineHCID 149329503-(1-Chloroethyl)pyridine

Product 1

HCID 178488322HCID 178488322, compound

Reagents, catalysts & solvents 3

HCID 4875Potassium IodideReagentHCID 10796Cesium carbonateReagentHCID 6228DimethylformamideSolvent3×

Conditions

Temperature
70 °C

Workup

  1. aliquotNo procedure recorded
  2. additionDilution of the aliquot (2 uL) with DMSO (200 uL).

Sources & evidence

ORD record
ord-1b91150512314600894225b56f72acda
Source dataset
Fig 7 data from Golden paper
Original link
View source

Reaction notes

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