1-(3-methoxyphenyl)-5-oxopyrrolidine-3-carboxylic acid → HCID 178490794, compound

HRID 1581400Notes

Reaction equation

HRID 1581400 reaction equation
CC(Cl)c1cccnc1.COc1cccc(N2CC(C(=O)O)CC2=O)c1>CN(C)C=O.O=C([O-])[O-].[Cs+].[Cs+].[I-].[K+]>COc1cccc(N2CC(C(=O)OC(C)c3cccnc3)CC2=O)c1

Participants

6

Reactant 2

HCID 29189441-(3-methoxyphenyl)-5-oxopyrrolidine-3-carboxylic acidHCID 149329503-(1-Chloroethyl)pyridine

Product 1

HCID 178490794HCID 178490794, compound

Reagents, catalysts & solvents 3

HCID 4875Potassium IodideReagentHCID 10796Cesium carbonateReagentHCID 6228DimethylformamideSolvent3×

Conditions

Temperature
70 °C

Workup

  1. aliquotNo procedure recorded
  2. additionDilution of the aliquot (2 uL) with DMSO (200 uL).

Sources & evidence

ORD record
ord-a87e753fe7e64be181886dcbc23bc63a
Source dataset
Fig 7 data from Golden paper
Original link
View source

Reaction notes

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