5-methyl-1-(2-methylphenyl)-1H-pyrazole-4-carboxylic acid → HCID 178424337, compound

HRID 1581434Notes

Reaction equation

HRID 1581434 reaction equation
CC(Cl)c1cccnc1.Cc1ccccc1-n1ncc(C(=O)O)c1C>CN(C)C=O.O=C([O-])[O-].[Cs+].[Cs+].[I-].[K+]>Cc1ccccc1-n1ncc(C(=O)OC(C)c2cccnc2)c1C

Participants

6

Reactant 2

HCID 27797775-methyl-1-(2-methylphenyl)-1H-pyrazole-4-carboxylic acidHCID 149329503-(1-Chloroethyl)pyridine

Product 1

HCID 178424337HCID 178424337, compound

Reagents, catalysts & solvents 3

HCID 4875Potassium IodideReagentHCID 10796Cesium carbonateReagentHCID 6228DimethylformamideSolvent3×

Conditions

Temperature
70 °C

Workup

  1. aliquotNo procedure recorded
  2. additionDilution of the aliquot (2 uL) with DMSO (200 uL).

Sources & evidence

ORD record
ord-19f1549ea6f44eae96973699b7e6d0a0
Source dataset
Fig 7 data from Golden paper
Original link
View source

Reaction notes

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