Piperidin-4-ol → HCID 10309418, compound

HRID 1581471Notes

Reaction equation

HRID 1581471 reaction equation
[OH:1][CH:2]1[CH2:7][CH2:6][NH:5][CH2:4][CH2:3]1.C([O:15][C:16](=O)[NH:17][C:18]1[S:22][C:21]2[C:23]([C:29]3[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=3)=[CH:24][CH:25]=[C:26]([O:27][CH3:28])[C:20]=2[CH:19]=1)C1C=CC=CC=1>>[CH3:28][O:27][C:26]1[C:20]2[CH:19]=[C:18]([NH:17][C:16]([N:5]3[CH2:6][CH2:7][CH:2]([OH:1])[CH2:3][CH2:4]3)=[O:15])[S:22][C:21]=2[C:23]([C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)=[CH:24][CH:25]=1

Participants

3

Reactant 2

HCID 79341Piperidin-4-olHCID 20724759HCID 20724759, compound

Product 1

HCID 10309418HCID 10309418, compound

Procedure

The title compound MS: m/e=381.2 (M−H) was obtained as a light brown solid (54% yield) by the reaction of 4-hydroxy-piperidine with (4-methoxy-7-phenyl-benzo[b]thiophen-2-yl)-carbamic acid benzyl ester according to the method described above for example 1.

Sources & evidence

ORD record
ord-7516e98a82ac496bbb3ba357538f8345
Source dataset
uspto-grants-2004_05
Patent number
US06730670B2

Reaction notes

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