1-Methylpiperazine → HCID 10150508, compound

HRID 1581473Notes

Reaction equation

HRID 1581473 reaction equation
[CH3:1][N:2]1[CH2:7][CH2:6][NH:5][CH2:4][CH2:3]1.C(O[C:16](=[O:35])[NH:17][C:18]1[S:22][C:21]2[C:23]([C:29]3[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=3)=[CH:24][CH:25]=[C:26]([O:27][CH3:28])[C:20]=2[CH:19]=1)C1C=CC=CC=1>>[CH3:28][O:27][C:26]1[C:20]2[CH:19]=[C:18]([NH:17][C:16]([N:5]3[CH2:6][CH2:7][N:2]([CH3:1])[CH2:3][CH2:4]3)=[O:35])[S:22][C:21]=2[C:23]([C:29]2[CH:30]=[CH:31][CH:32]=[CH:33][CH:34]=2)=[CH:24][CH:25]=1

Participants

3

Reactant 2

HCID 531671-MethylpiperazineHCID 20724759HCID 20724759, compound

Product 1

HCID 10150508HCID 10150508, compound

Procedure

The title compound MS: m/e=380.2 (M−H) was obtained as a light yellow foam (46% yield) by the reaction of N-methyl-piperizine with (4-methoxy-7-phenyl-benzo[b]thiophen-2-yl)-carbamic acid benzyl ester according to the method described above for example 1.

Sources & evidence

ORD record
ord-74a6b6c2c7dd42ff84f967af9fab7df1
Source dataset
uspto-grants-2004_05
Patent number
US06730670B2

Reaction notes

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