Hydrochloric Acid → 6-Oxo-1,6-dihydro-pyridazine-3-sulfonic Acid methyl-phenyl-amide

Participants

Reaction Steps

A mixture of 6-methoxy-pyridazine-3-sulfonic acid methyl-phenyl-amide (239 mg), dioxane (4 mL) and concentrated hydrochloric acid (1 mL) was prepared and refluxed for one hour. The mixture was then evaporated to dryness. The resulting solid was triturated with water and the solid was collected to afford the title compound (75%, 171 mg); mp, 157-158° C.

Provenance & Evidence