HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chlorobenzylamine → HCID 22722034, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chlorobenzylamine | HCID 66036 | — |
| Reactant | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Reactant | 1-Hydroxybenzotriazole hydrate | HCID 2796029 | — |
| Reactant | HCID 22722031 | HCID 22722031 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 22722034 | HCID 22722034 | — |
Reaction Steps
A mixture of 6-bromo-4-hydroxyisoquinoline-3-carboxylic acid (Preparation 8, 0.4 g), 4-chlorobenzylamine (0.219 g), 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (0.305 g) and 1-hydroxybenzotriazole monohydrate (0.217 g) in DMF (20 mL) is stirred at room temperature until judged complete. The solution is then poured into ice water and the resulting solid collected and dried.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06730682B2 |
| Source dataset | uspto-grants-2004_05 |
| ORD ID | ord-127e6fb516f144a4b614727e02d002c7 |
| Source note | uspto-grants-2004_05 |