HuagongsheHuagongshe Chemistry Print Report · For research reference only
4'-Hydroxyacetophenone → HCID 66935305, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4'-Hydroxyacetophenone | HCID 7469 | — |
| Reactant | 3-(1,2-Oxazol-5-yl)phenol | HCID 22723471 | — |
| Reactant | HCID 66935305 | HCID 66935305 | — |
| Reactant | HCID 69517765 | HCID 69517765 | — |
| Product | HCID 66935305 | HCID 66935305 | — |
| Product | Phenol, 4-(5-isoxazolyl)- (9CI) | HCID 135744209 | — |
Reaction Steps
3-(Dimethylamino)-1-(4-hydroxyphenyl)-2-propen-1-one is prepared from 4-hydroxyacetophenone substantially in the same manner as that described for 3-(dimethylamino)-1-(3-hydroxyphenyl)-2-propen-1-one (Epoxide 24). 4-(5-Isoxazolyl)phenol is prepared from 3-(dimethylamino)-1-(4-hydroxyphenyl)-2-propen-1-one substantially in the same manner as that described for 3-(5-isoxazolyl)phenol (Epoxide 25). This phenolic product is reacted with (2S)-glycidyl 3-nitrobenzenesulfonate substantially as described for Epoxide 1 to yield the title epoxide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06730792B2 |
| Source dataset | uspto-grants-2004_05 |
| ORD ID | ord-6ce122e7c9b343baa0ac764e679d5425 |
| Source note | uspto-grants-2004_05 |