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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1581798Generated: October 31, 2026

HCID 22723464, compound → HCID 22723455, compound

https://huagongshe.com/reaction/1581798

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 22723464HCID 22723464—
CatalystPalladiumHCID 23938—
SolventDichloromethaneHCID 6344—
ProductHCID 22723455HCID 2272345590%

Reaction Steps

To a solution of the oxazole from above (1.99 g, 7.92 mmol) in dichloromethane (20 ml) is added 10% palladium on carbon (1.99 g). The mixture is put under an atmosphere of hydrogen, stirred at room temperature over night, then filtered through Celite. The solvent is removed under reduced pressure to leave 2-(oxazol-4-yl)phenol (1.15 g, 90%), which is used for the next step without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06730792B2
Source datasetuspto-grants-2004_05
ORD IDord-28d2c149803b48fca9e0788fac35463b
Source noteuspto-grants-2004_05