HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 22723464, compound → HCID 22723455, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 22723464 | HCID 22723464 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 22723455 | HCID 22723455 | 90% |
Reaction Steps
To a solution of the oxazole from above (1.99 g, 7.92 mmol) in dichloromethane (20 ml) is added 10% palladium on carbon (1.99 g). The mixture is put under an atmosphere of hydrogen, stirred at room temperature over night, then filtered through Celite. The solvent is removed under reduced pressure to leave 2-(oxazol-4-yl)phenol (1.15 g, 90%), which is used for the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06730792B2 |
| Source dataset | uspto-grants-2004_05 |
| ORD ID | ord-28d2c149803b48fca9e0788fac35463b |
| Source note | uspto-grants-2004_05 |