Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Iodine | HCID 807 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 2-Bromo-9H-fluorene | HCID 14336 | — |
| Reactant | Iodic acid | HCID 24345 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-Bromo-7-iodo-9H-fluorene | HCID 14290982 | 317% |
Reaction Steps
A mixture of 2-bromofluorene (12.61 g, 50 mmol), acetic acid (125 mL), water (9 mL), concentrated sulfuric acid (4 mL), iodine (5.1 g, 20.1 mmol) and iodic acid (2.2 g, 12.5 mmol) was heated at 80-90° C. for 2 hours, cooled and filtered. The solids were washed with acetic acid (100 mL) and water (500 mL), to get the product 14.7 g (79% yield), m.p. 179-185° C. Mass Spec. (m/z): 418 (M+ diiodo), 370, 372 (M+iodobromo), 322, 324, 326 (M+ dibromo).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06730793B1 |
|---|
| Source dataset | uspto-grants-2004_05 |
|---|
| ORD ID | ord-ab7d9b625eb6423f9f15f925eddfbb72 |
|---|
| Source note | uspto-grants-2004_05 |
|---|
