反应详情

温度

85 °C

A mixture of 2-bromofluorene (12.61 g, 50 mmol), acetic acid (125 mL), water (9 mL), concentrated sulfuric acid (4 mL), iodine (5.1 g, 20.1 mmol) and iodic acid (2.2 g, 12.5 mmol) was heated at 80-90° C. for 2 hours, cooled and filtered. The solids were washed with acetic acid (100 mL) and water (500 mL), to get the product 14.7 g (79% yield), m.p. 179-185° C. Mass Spec. (m/z): 418 (M+ diiodo), 370, 372 (M+iodobromo), 322, 324, 326 (M+ dibromo).

1. temperaturecooled
2. filtrationfiltered
3. washThe solids were washed with acetic acid (100 mL) and water (500 mL)