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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1581981Generated: October 25, 2026

Formamide → HCID 178435036, compound

https://huagongshe.com/reaction/1581981

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFormamideHCID 713—
ReactantEthyl 2-amino-4,5-dimethyl3-thenoateHCID 78536—
ProductHCID 178435036HCID 178435036—

Reaction Steps

Using ethyl 2-amino-4,5-dimethylthiophene-3-carboxylate (500 mg, 2.5 mmol) and formamide (5 ml), a similar procedure to a) in Example 19 was carried out to obtain 4-hydroxy-5,6-dimethylthieno[2,3-d]pyrimidine (380 mg, 2.1 mmol) having the following physical properties:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06734180B1
Source datasetuspto-grants-2004_05
ORD IDord-78d722231274482c99204a4c0e4a3722
Source noteuspto-grants-2004_05