反应详情

Following General Procedure C, 6-isopropyl-4,4-dimethyl-1-ethyl-1,2,3,4-tetrahydro-quinoline-8-carbaldehyde (Intermediate 7, 5.78 g, 26 mmol) and a solution of ethyl magnesium bromide (2M, 35 ml, 65 mmol) in THF were reacted to give the title compound as a yellow oil after purification by column chromatography using 5% ethyl acetate in hexane.