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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1582491Generated: October 31, 2026

Propylene Oxide → HCID 22721141, compound

https://huagongshe.com/reaction/1582491

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPropylene OxideHCID 6378—
ReactantHCID 22721056HCID 22721056—
SolventMethanolHCID 887—
ProductHCID 22721141HCID 22721141—

Reaction Steps

The compound was prepared by the treatment of [4,5-bis-(4-chloro-phenyl)-2-(2-isopropoxy-4-methoxy-phenyl)-4,5-dihydro-imidazol-1-yl]-piperazin-1-yl-methanone (example 10 g) with propylene oxide in methanol for 7 h at 45° C. in a sealed tube. HR-MS (ES, m/z) calculated for C33H38N4O4Cl2[(M+H)+]625.2343, observed 625.2350.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06734302B2
Source datasetuspto-grants-2004_05
ORD IDord-1cac39a901874c008f91fa74f7e7b9d9
Source noteuspto-grants-2004_05