Hydrochloric Acid → HCID 69866354, compound

HRID 1582536Notes

Reaction equation

HRID 1582536 reaction equation
[CH2:1]([CH:3]1[C:12]2[CH:11]=[C:10]3[N:13]([CH3:20])[C:14](=[O:19])[CH:15]=[C:16]([O:17]C)[C:9]3=[CH:8][C:7]=2[NH:6][CH2:5][CH2:4]1)[CH3:2].Cl.C([O-])(=O)C.[Na+]>>[CH2:1]([CH:3]1[C:12]2[CH:11]=[C:10]3[N:13]([CH3:20])[C:14](=[O:19])[CH:15]=[C:16]([OH:17])[C:9]3=[CH:8][C:7]=2[NH:6][CH2:5][CH2:4]1)[CH3:2]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 517045Sodium AcetateHCID 22717653HCID 22717653, compound

Product 1

HCID 69866354HCID 69866354, compound

Procedure

0.5 g (1.8 mmol) of 9-ethyl-4-methoxy-1-methyl-6,7,8,9-tetrahydropyrido[2,3-g]quinol-2-one in 5 ml of 10% strength hydrochloric acid is heated to reflux for 2 h. The suspension is neutralized to pH 5 using 10% strength sodium acetate solution. The precipitate is filtered off with suction and dried in a desiccator.

Workup

  1. temperatureto reflux for 2 h
  2. filtrationThe precipitate is filtered off with suction
  3. customdried in a desiccator

Sources & evidence

ORD record
ord-ea9824189b3c429aa06f2a554d2ae837
Source dataset
uspto-grants-2004_05
Patent number
US06737280B1

Reaction notes

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