HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Chloro-2-phenylethane → 1-(5-chloro-2-(phenethyloxy)phenyl)-1-cyclopropyl-2-(1H-1-imidazolyl)-1-ethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Chloro-2-phenylethane | HCID 231496 | — |
| Reactant | 4-chloro-2-(1-cyclopropyl-1-hydroxy-2-(1H-1-imidazolyl)ethyl)phenol | HCID 12972899 | — |
| Product | 1-(5-chloro-2-(phenethyloxy)phenyl)-1-cyclopropyl-2-(1H-1-imidazolyl)-1-ethanol | HCID 12972907 | 26.4% |
Reaction Steps
The general procedure of Example 6 was repeated using 4-chloro-2-(1-cyclopropyl-1-hydroxy-2-(1H-1-imidazolyl)ethyl)phenol [compound (2-3)] and phenethyl chloride, to thereby yield 1-(5-chloro-2-(phenethyloxy)phenyl)-1-cyclopropyl-2-(1H-1-imidazolyl)-1-ethanol as colorless crystals (yield: 26.4%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06737434B2 |
| Source dataset | uspto-grants-2004_05 |
| ORD ID | ord-b4289f35ac3e49239e7a3376ec00dc88 |
| Source note | uspto-grants-2004_05 |