Aluminium lithium hydride → HCID 69475784, compound

HRID 1582690Notes

Reaction equation

HRID 1582690 reaction equation
[H-].[H-].[H-].[H-].[Li+].[Al+3].[C:7]([OH:12])(=O)[CH:8]=[CH:9][CH3:10].[C:13]1([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>C1COCC1>[C:13]1([C:19]2[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=2)[CH:18]=[CH:17][C:16]([C:9]([CH3:10])=[CH:8][CH2:7][OH:12])=[CH:15][CH:14]=1

Participants

4

Reactant 2

HCID 21226445Aluminium lithium hydrideHCID 86591447HCID 86591447, compound

Product 1

HCID 69475784HCID 69475784, compoundYield 40.6%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

LiAlH4 reduction of ethyl 3-([1,1′-biphenyl]-but-2-enoate (3e) using THF as solvent under similar conditions furnished 40.6% yield of 3-([1,1′-biphenyl]-4yl)-2-butenol (4e).

Sources & evidence

ORD record
ord-17ed9bfad3d543e284aeae714e74d343
Source dataset
uspto-grants-2004_05
Patent number
US06737438B2

Reaction notes

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