Hydrochloric Acid → 5-Nitro-1-aminonaphthalene hydrochloride

Participants

Reaction Conditions

Reaction Steps

In a 100 mL flask equipped with a reflux condenser, an inlet tube for hydrogen chloride gas and a thermometer were placed 2.1 g of 5-nitro-1-tetralone oxime and 40 mL of acetic acid. While bubbling hydrogen chloride gas, the mixture was heated at 100° C. for 4 hours with stirring by a stirring bar. After allowing the mixture to be cooled to room temperature, a precipitated 5-nitro-1-aminonaphthalene hydrochloride was collected by filtration and rinsed with a small amount of acetic acid. After drying in vacuo, 5-nitro-1-aminonaphthalene hydrochloride (1.0 g) was obtained. No naphthalene derivatives isomerized in the amino or nitro group were detected.

Provenance & Evidence